Diltiazem-Associated Hyperpigmentation

Diltiazem-associated photodistributed hyperpigmentation: a review of 4 cases.

BACKGROUND Diltiazem hydrochloride is a widely used calcium channel blocking agent. While a few cases of diltiazem-associated photosensitivity have been reported, no cases of photodistributed hyperpigmentation are known. OBSERVATION Four cases of photodistributed hyperpigmentation associated with the long-acting formulation of diltiazem hydrochloride (Cardizem CD) are presented. All patients ...

Chemotherapy-associated supravenous hyperpigmentation.

Amlodipine associated hyperpigmentation.

Amlodipine is a potent peripheral and coronary vasodilator with high selectivity for vascular smooth muscle, and is widely used in mild to moderate hypertension, chronic stable angina and vasospastic angina. Its most prevalent side effects are peripheral edema, flushing and headache. Cutaneous adverse reactions associated with amlodipine have been rarely reported. Herein, a male patient is desc...

Depression associated with diltiazem.

I Selsin BI.. Systemic effects of topical ophthalmic medications. South MedJ7 1983;76:349-58. 2 Hayes LP, Stewart CJ, Kim I, Mohr JA. Timolol side effects and inadvertent overdosing. JAmGeiatr Soc 1989;37:261-2. 3 Pringle SD, MacEwen CJ. Severe bradvcardia due to interaction of timolol eyedrops and verapamil. BrMedJ 1987;294:155-6. 4 Falbe WJ, Boyd DL. Homatropine-associated confusion in an eld...

Tongue hyperpigmentation associated with chemotherapy

W e demonstrate a new hyperpigmentation on the tongue of a 68-year-old female patient who was diagnosed with stage IIA infiltrating ductal carcinoma of the left breast who underwent modified radical mastectomy followed by a triple chemotherapy regimen which consisted of doxorubicin, docetaxel, and cyclophosphamide. The patient developed the tongue hyperpigmentation a few weeks after the initiat...